If you’re looking for a holiday apartment in one of Rome’s livelier neighbourhoods that’s also close to some of the city’s attractions, then staying in the multicultural Esquilino district is your best option. Both the Santa Maria Maggiore church and the Piazza Vittorio Emmanuele II (the largest square in Europe) are located here. For getting around, you’ve also got the Termini station up in the northern part of the district, which is ideal for travellers who need to catch an early train.