Booking a hotel room near the Arch of Constantine is a great idea if you're looking to really immerse in ancient Roman culture. The area nearby is full of famous ancient Roman monuments such as the Coliseum. What's more there are good transport connections for the rest of the city.
Inaugurated in 315 AD this 20m high arch, located next to the Roman Coliseum, was erected in memory of the victory of Constantine against Maxentius